Testingprovides a biochemical
snap shot of your body.

is the studyof how our environment
effects our genes.

Welcome to
Elemental Health
& Nutrition

medicineacknowledges that every person
is uniquely different to the next

Medicinestudies the therapeutic
value of nutrients

“Your perspective
is always limited... by how much you know.
Expand your knowledge and you will transform your mind.” - Bruce Lipton

Methylation and Nutrigenomics

The methylation cycle is a system that recycles homocysteine and creates SAMe (s-adenosylmethionine), which has enormous consequences.
SAMe is is the body’s universal methyl donor and is responsible for over 250 enzymatic reactions in the body. Methylation is the process of transferring methyl groups from one place to another, but there are many reasons why these groups cannot be passed freely. It may be from not having enough vitamin B12, having hypothyroidism, having high amounts of inflammation in the body, or by having a genetic predisposition.

On average, 45% of the population have a genetic error for an enzyme called MTHFR (methyltetrahydrofolate reductase). This enzyme is essential to pass methyl groups to other substrates, and most importantly to convert folate into 5-MTHF (5-methyltetrahydrofolate), which is an active form of folate.

Errors in this gene can cause a variety of symptoms and heath conditions, including the following;

  • Autism
  • Addictions
  • Down’s syndrome
  • Miscarriages
  • Pulmonary embolisms
  • Depression
  • Schizophrenia
  • Fibromyalgia
  • Chronic Fatigue Syndrome
  • Chemical Sensitivity
  • Parkinson’s
  • Irritable Bowel Syndrome
  • Pre-eclampsia
  • Stroke
  • Bipolar disorder
  • Colorectal Adenoma
  • Male infertility
  • Blood clots
  • Congenital Heart Defects
  • Deficits in childhood development
  • Gastric Cancer
  • Migraines with aura
  • Low HDL
  • High homocysteine
  • Post-menopausal breast cancer
  • Atherosclerosis
  • Oral Clefts
  • Type 1 Diabetes
  • Epilepsy
  • Alzheimer’s
  • Decreased telomere length
  • Cervical dysplasia
  • Increased bone fracture risk in post-menopausal women
  • Multiple Sclerosis
  • Hypertension
  • Thyroid Carcinoma
  • Prostate Cancer
  • Placental Abruption
  • Heart Attacks
  • Methotrexate Toxicity
  • Nitrous Oxide Toxicity
  • Heart Murmurs
  • Tongue Tie
  • Behcet’s Disease
  • Ischemic Stroke in Children
  • Unexplained Neurologic Disease
  • Asthma
  • Shortness of Breath
Other genetic SNPs (single nucleotide polymorphisms) can also influence how the methylation cycle operates. CBS, COMT, MAO-A, SHMT, MTR, MTRR, VDR and BHMT are just to name a few, and they all interact in a delicately precise manner.

Epigenetics is a recent field of medicine that looks at how our external environment and lifestyle choices can influence our genes. We are not destined to have the health of our parents or grandparents. We may have the same genes, with the same risk of certain conditions, but we can influence the expression of these genes by how we live our lives; by the food we eat, the toxins we’re exposed to, the thoughts we have, the exercise we chose, and the relationships we engage in. We govern our genes, not the other way around.
ChromosomeNutrigenomics studies how using particular nutrients can alter the expression of our genes. By using dedicated nutrients which the body normally requires for proper function, we can get our genetic mechanics back on track. Methylation requires certain substrates, enzymes, and co-factors to run effectively. For example, an individual with low levels of serine, vitamin B6, and molybdenum may react badly to sulphur, or have trouble dealing with environmental toxins. By reinstating the body with these nutrients, the health of the person can come back into alignment with what it should be.

Treating a person with a SNP involves taking a thorough case history and analysing their symptoms, lifestyle and environmental influences. Testing for the MTHFR gene can be done during a session, and other testing parameters can also be used when required. Quite often a referral to the doctor for blood tests is recommended, which provides an inexpensive way to gain a lot of insightful information that can direct treatment.

Genetic SNPs are a part of life; none of us are perfect; but we can do our best to find out how our bodies are operating and give them the best chance of reaching their potential.

So you have MTHFR, what’s next?….